Forward-Time Population Genetics Simulations

Methods, Implementation, and Applications

By Bo Peng, Christopher I. Amos, Marek Kimmel | Publisher: Wiley

About the book

The only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies

The rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. Forward-Time Population Genetics Simulations presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators.

The book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics.

Forward-Time Population Genetics Simulations includes:

  • An overview of currently available forward-time simulation methods, their advantages, and shortcomings

  • An overview and evaluation of currently available software

  • A simuPOP tutorial

  • Applications in population genetics

  • Applications in genetic epidemiology, statistical genetics, and mapping complex human diseases

The only book of its kind in the field today, Forward-Time Population Genetics Simulations will appeal to researchers and students of population and statistical genetics.

Editions of Forward-Time Population Genetics Simulations

Paperback
ISBN 9780470503485
EBook
ISBN 9781118180358
EBook
ISBN 9781118180341

Read an Excerpt

The only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies

The rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. Forward-Time Population Genetics Simulations presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators.

The book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics.

Forward-Time Population Genetics Simulations includes:

  • An overview of currently available forward-time simulation methods, their advantages, and shortcomings

  • An overview and evaluation of currently available software

  • A simuPOP tutorial

  • Applications in population genetics

  • Applications in genetic epidemiology, statistical genetics, and mapping complex human diseases

The only book of its kind in the field today, Forward-Time Population Genetics Simulations will appeal to researchers and students of population and statistical genetics.

Frequently Asked Questions

What is Forward-Time Population Genetics Simulations about?

The only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies

The rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. Forward-Time Population Genetics Simulations presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators.

The book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics.

Forward-Time Population Genetics Simulations includes:

  • An overview of currently available forward-time simulation methods, their advantages, and shortcomings

  • An overview and evaluation of currently available software

  • A simuPOP tutorial

  • Applications in population genetics

  • Applications in genetic epidemiology, statistical genetics, and mapping complex human diseases

The only book of its kind in the field today, Forward-Time Population Genetics Simulations will appeal to researchers and students of population and statistical genetics.

What core themes, tropes, or subjects are explored in Forward-Time Population Genetics Simulations?

Mathematics and Science > Biology, life sciences > Life sciences: general issues > Genetics (non-medical)

Where can I read a sample of Forward-Time Population Genetics Simulations?

You can read an official preview of the few pages here https://www.book2look.com/book/9780470503485

Who is/are the Author/s of the book Forward-Time Population Genetics Simulations?

Bo Peng, Christopher I. Amos, Marek Kimmel

Who is the Publisher of the book Forward-Time Population Genetics Simulations?

Wiley

What are the ISBN numbers for the physical and digital editions?

Forward-Time Population Genetics Simulations is available as paperback(ISBN 9780470503485) and ebook(ISBN 9781118180358) and ebook(ISBN 9781118180341)

Where can I buy Forward-Time Population Genetics Simulations online or support local independent bookshops?

You can buy Forward-Time Population Genetics Simulations from below

Where can I buy Forward-Time Population Genetics Simulations?